When the response was defined by PaO2/FiO2 ratio, no significant differences in Pplat, PaCO2 or VDalv/VT alterations between responders (n = 7) and nonresponders (n = 6) were observed. Changes in VDalv/VT were correlated with changes in Crs, but not with changes in PaO2/FiO2 ratios. Maximal changes were observed after six to nine hours. PP induced a decrease in Pplat, PaCO2 and VDalv/VT ratio and increases in PaO2/FiO2 ratios and compliance of the respiratory system (Crs).
Estimated and measured VDphysiol/VT ratios were compared. Thirteen patients with a PaO2/FiO2 ratio 20 mmHg or by a decrease in PaCO2 > 2 mmHg. We also aimed to validate a recently proposed method of estimation of the physiological dead space (VDphysiol/VT) without measurement of expired CO2. routine exercise test, where blood gas evaluation is done essentially by means of arterialized earlobe capillary sampling.Our aims in this study were to report changes in the ratio of alveolar dead space to tidal volume (VDalv/VT) in the prone position (PP) and to test whether changes in partial pressure of arterial CO2 (PaCO2) may be more relevant than changes in the ratio of partial pressure of arterial O2 to fraction of inspired O2 (PaO2/FiO2) in defining the respiratory response to PP.intensive care patients, equipped, for their routine clinical care, with an arterial line this allows for a precise timed comparison between PaCO2 and PtCO2 readouts.The evaluation will be done in 2 different settings: Validity of this measurement needs to be assessed against arterial sampling (either arterial, or arterialized capillary), especially with regards to the lag time required by the CO2 diffusion from the arterial compartment (PaCO2) to the cutaneous one (PtCO2), in particular when rapid changes of CO2 might be induced by exercise. The study aim is to monitor, during exercise tests carried out in various conditions, the alveolar dead space, by means of continuous transcutaneous measurement of Pt CO2, which would be used as a surrogate for arterial PaCO2. Why Should I Register and Submit Results?.
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